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However, genetic analysis may not always detect pathogenic mutations that are due to mosaicism or unidentified epigenetic factors (71)
d , Quantification of MitoSOX red fluorescence in animals as depicted in ( c )
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Sorafenib upregulates ABCC5 via the PI3K/Akt/Nrf2 pathway, which inhibits lipid peroxidation-mediated ferroptosis and promotes cancer growth, resulting in acquired sorafenib resistance in human HCC cells, according to Huang et al (91)
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