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This association remained significant even after adjusting for age, BMI, and other potential confounders [1]
For Galvin, thats the real win
This suggests that LC administration prevents muscle loss not just by lowering UPS activity, but also by preventing actomyosin complex disassociation, which is essential for the UPS to break down the monomeric contractile proteins (Vescovo et al., 2002)
In future work, extensive in vitro and in vivo studies can be conducted with the identified selective 3-MST inhibitors, providing a basis for the treatment of cancer, cardiovascular, and neurological diseases
J Urol 213:e328 Feghali K, Li X, Maalouf NM (2024) Changes in 24-hour urine chemistry in patients with nephrolithiasis during weight loss with glucagon-like peptide 1-based therapies
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