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treated cells were incubated with JC-1 dye (5 g/mL) for 30 min at 37 C, followed by fluorescence detection using a fluorescence microscope, where the red/green fluorescence ratio was calculated to quantify mitochondrial polarization status, as a higher ratio indicates healthier mitochondrial function while a lower ratio suggests mitochondrial depolarization and dysfunction

Drugs that are prescribed to treat type 2 diabetes may be covered under Medicare Part D or Medicare Advantage plans

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15,20 Although many of these AEs have occurred early in therapy and subsided over time, they remain a primary reason for dose adjustment or discontinuation

Not Getting Enough Nutrients: Some people find that these medications suppress their appetite so much that theyre not eating enough