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Losing 5% to 10% of body weight through diet and exercise has been associated with a reduced risk of cardiovascular disease in adults who are obese or overweight

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Standen BT, Peggs DL, Rawling MD, Foey A, Davies SJ, Santos GA, Merrifield DL (2016) Dietary administration of a commercial mixed-species probiotic improves growth performance and modulates the intestinal immunity of tilapia, Oreochromis niloticus

If that's the case, you can build up your tolerance by adding fiber to your diet slowly