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Glutathione peroxidase 4 is a predictor of diabetic kidney disease progression in type 2 diabetes mellitus

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Notably, no Grade 3 adverse events were observed, consistent with anlotinibs known safety profile (e.g., Grade 12 triglyceride elevation, hypertension, hand-foot syndrome, oral mucositis, and fatigue) (12)

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The literature survey reveals that there exists some conventional analytical method development of these drugs individually through HPLC [3,4,5,6,7,8,9,10,11,12], UV [13,14,15] and HPTLC [16, 17]