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Third generation: multi-receptor agonists Tirzepatide targets both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors simultaneously, producing greater metabolic effects than GLP-1 alone: Mounjaro , once-weekly injection for type 2 diabetes (FDA-approved 2022)

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Sanofi has the largest patent position in the field and no disclosed clinical program, which means either an undisclosed asset or a very deliberate royalty strategy

*Correspondence: Mohammad Hosein Farzaei, [email protected]