Up to now, researchers have explored and developed some new agents for RA according to these classical or emerging targets
Benfotiamine is a highly bioavailable form of vitamin B1 that: Decreases oxidative stress Improves nerve conduction Inhibits neurodegeneration Relevant Research YK-11 regulates myogenic differentiation of C2C12 myoblasts by follistatin expression Myostatin inhibitor YK-11 as a preventative health supplement for bacterial sepsis MK-677 Elsevier reported that 25 mg/day of MK-677, administered over two 14-day periods, did not cause any notable side effects (Murphy et al., 1998)
doi: 10.5435/JAAOSGlobal-D-25- 6: Mayfield CK, Bolia IK, Feingold CL, Lin EH, Liu JN, Rick Hatch GF, Gamradt SC, Weber AE
Some preliminary study shows that vitamin B12 benefits the body immune system enough to possibly assist prevent cancer cells, including cervical, prostate and also colon cancers
There was no significant difference in vasorelaxation induced by 0.1 or 1 g/ml BPC 157 in aorta without endothelium