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I have personally used variations of this stack for over a decade and the impact on skin quality especially on the face and neck is both measurable and visible

In December 2023, Pfizer discontinued the twice-daily formulation due to tolerability issues, and in June 2024, the once-daily version failed to meet efficacy and tolerability targets

Having more options available to patients is a good thing, says Daniel Drucker, an endocrinologist at the University of Toronto whose research paved the way for GLP-1 drugs but who was not involved in the new studies

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