The choice between medications should rest primarily on efficacy data, tolerability, availability, and cost rather than the B12 inclusion, which is valuable in both formulations
Why stopping and starting can be risky For many patients, stopping is not really a choice
Asher MI, Keil U, Anderson HR, Beasley R, Crane J, Martinez F, Mitchell EA, Pearce N, Sibbald B, Stewart AW, Strachan D, Weiland SK, & Williams HC (1995) International study of asthma and allergies in childhood (ISAAC): Rationale and methods
Whitmore KE, Theoharides TC
Despite the absence of improvement in the primary endpoint, noteworthy findings were reported, including a significant reduction in manifestations such as bloating, nausea, postprandial fullness, and bellyache