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The visual model fit was evaluated using standard goodness-of-fit (GOF) criteria, reductions in the objective function value (OFV) for nested models, Akaike information criteria (AIC) and Bayesian information criteria (BIC) for non-nested models, and acceptable precision of estimates ( 2 -test, p 10.83 ( 2 -test, p 1.88 ng/mL was observed according to the Monte Carlo simulation results

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Compared with other MPS inhibition strategies, inhibition of energy metabolism did not eliminate macrophages and was beneficial to the recovery of immune function