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While zinc deficiency leads to systemic impairment of biological processes, zinc excess exerts its toxicity primarily through the competitive inhibition of the absorption of other essential minerals (e.g., Cu and Fe) and the disruption of the gut microbial ecology, potentially promoting antibiotic resistance

The company said 10 Phase III trials with PF-08653944 were expected to advance in 2026

Night sweats were waking me up three to four times a night