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Women of childbearing potential should use effective contraception, and semaglutide should be discontinued at least 2 months before a planned pregnancy

Magnitud del efecto es la diferencia ms significativa

doi: 10.1038/s41598-025-12644-w 178 WangYWeiXWuM

In normal pancreas, pancreatic cells expressed GLP-1R, with only low expression in acinar cells, whereas in AP or CP, acinar cells, ductal cells and activated PSCs expressed GLP-1R

Cells were plated on top of the 0.6% Bacto agar layer in glucose and glutamine free DMEM media containing 10 mM glucose and 4 mM glutamine and supplemented with 10% FS and 0.3% Bacto Agar