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Glypican-4 enhances insulin signaling via interaction with the insulin receptor and serves as a novel adipokine

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Understanding the difference between GLP-1 and dual GLP-1/GIP agonists like Zepbound and Mounjaro is essential

While standardized clinical assays are still needed, integrating mtDNA metrics into patient management holds promise for advancing personalized medicine in HIV care, shifting the focus from viral suppression to the optimization of metabolic and immunological health 7 Therapeutic strategies targeting mitochondria and mtDNA The recognition of mitochondrial dysfunction as a cornerstone of HIV pathogenesis and ART-related toxicity has catalyzed the search for therapeutic strategies aimed at preserving or restoring mitochondrial health

On the other hand, CatB inhibitors may avert HAND, TBI, and cancer (Ha et al., 2012