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Energy metabolism, which is critical for each organism, was significantly reduced in AST1D rats, especially in serum and hippocampus

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36415 Routine venipuncture for blood tests

Although the mechanisms through which astrocytes maintain BBB integrity are not fully understood, there are several proposed astrocytic-derived soluble factors that may induce vital aspects of the BBB including interleukin-6 (IL-6), glial cell line-derived neurotrophic factor (GDNF), basic fibroblast growth factor (bFGF), fibroblast growth factor 2 (FGF-2), angiopoetin 1 (ANG1), and TGF [45, 46]