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For chronic weight management, tirzepatide works by engaging multiple hormonal pathways, including the GIP and GLP-1 receptors, which are crucial for metabolic regulation, blood sugar control, appetite management, and energy expenditure

Figure 2 2 Data of efficacy 2.1 Clinical trials: the SURPASS program The central clinical trial program designed to demonstrate the therapeutic effectiveness (in terms of GC and BW reduction), tolerability and safety of TZP in diabetic patients was the SURPASS program

More fat means more conversion, leaving less testosterone available

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