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doi: 10.1093/humrep/dex044 8 WaltersKABertoldoMJHandelsmanDJ

Although NSAIDs are effective in relieving the pain of chronic disorders, their long-term use is associated with a number of adverse effects , including GI bleeding, peptic ulcers, and renal and hepatic dysfunction

Examples of affected drugs include citalopram, antiarrhythmics (such as propafenone, flecainide), antidepressants (such as desipramine, paroxetine, fluoxetine, sertraline), antipsychotics (such as haloperidol, thioridazine), beta-blockers (such as metoprolol), among others

ML226 sometimes appeared to increase total OGDH-E2 levels

Note the timing of symptoms, foods, and stressors so your care team can help you adjust