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The efficacy of Fer-1 in mice with Bet v 1-induced asthma further suggests that the lipid peroxidation stress may amplify the inflammatory response

Importantly, the stability of BCHep analogues in MLMs was not affected by the presence of ANF, demonstrating that the bioisosteres successfully avoid the CYP1A-mediated metabolism that is responsible for hampering ezutromids sustained efficacy (Table 1)

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Zhang, The Growth Hormone Secretagogue Receptor: Its Intracellular Signaling and Regulation, Int